Preptide GHK-Cu Copper Peptide Moisturiser

The Pinnacle of Dermal Regeneration

In the pursuit of age-reversal and cellular health, the "Gold Standard" has officially turned Blue. Preptide GHK-Cu Moisturiser is more than a moisturizer; it is a bio-active signalling complex designed to communicate directly with your skin cells, triggering a cascade of renewal that standard skincare cannot reach.

By combining the legendary regenerative powers of Copper Tripeptide-1 (GHK-Cu) with our proprietary stabilization technology, we have created a formula that bridges the gap between clinical research and luxury skincare.

The Science of GHK-Cu: Why Your Skin Needs It

GHK-Cu is a naturally occurring copper complex that declines significantly as we age. By age 60, levels in the body drop by over 60%, leading to the structural collapse we recognize as wrinkles, thinning skin, and sagging.

When applied topically in our high-concentration formula, Preptide GHK-Cu acts as a "cellular commander." It signals fibroblasts to produce fresh collagen and elastin, restoring the architectural integrity of the dermal layer. Research shows it modulates genes involved in DNA repair to help reverse environmental damage, while simultaneously enhancing the proliferation of keratinocytes to speed up the skin’s natural renewal cycle. Originally used in wound healing, this peptide rapidly calms redness and repairs the skin barrier, making it ideal for sensitive skin or post-procedure recovery. 

The "Pretty Peptide": Inside Preptide GHK-Cu Dermal Science

GHK-Cu has earned its reputation as the "Pretty Peptide" not just for its striking natural cerulean hue, but for its unparalleled ability to reset the skin’s biological clock. Unlike traditional skincare that merely masks aging, Preptide GHK-Cu acts as a bio-identical signalling molecule. It communicates directly with DNA to downregulate inflammatory markers and upregulate the production of collagen, elastin, and glycosaminoglycans—the essential "scaffolding" that keeps skin firm, hydrated, and luminous.

What makes the Preptide formulation the definitive version of this peptide is our commitment to molecular stability. Copper peptides are notoriously fragile; if the pH of a serum is too acidic, the copper ion detaches from the peptide chain, rendering it useless. Preptide GHK-Cu is engineered within a Neutral pH (7.0) environment, ensuring the copper remains "chelated" (locked) within the peptide. This allows the "cellular commander" to arrive at the dermal layer fully intact, where it can effectively trigger the remodelling of scarred or aging tissue and promote the rapid regeneration of the skin barrier.

Beyond the copper peptide itself, our serum utilizes a Multi-Pathway Delivery System. We have fortified the "Pretty Peptide" with a synergistic blend of High-Molecular Weight Hyaluronic Acid for surface plumping and Liposomal Ceramides for deep-layer repair. This creates a dual-action effect: immediate glass-skin radiance on the surface and long-term structural thickening beneath. At Preptide, we don't believe in "beauty" as a superficial concept; we believe in beauty as a by-product of peak cellular health.

Why Preptide is the Industry Leader

The market is flooded with "copper" products, but most fail to deliver results. Preptide stands alone at the top through Clinical-Grade Concentration. While others use "Copper Gluconate" or trace amounts for colour, Preptide utilizes high-potency pure Copper Tripeptide-1 to ensure it reaches the deeper layers of the dermis.

Stability is our second pillar. Copper peptides are notoriously unstable, so our GHK-Cu is housed in a Neutral pH (7.0) calibrated base—the same rigorous standard used for our research-grade injectables—ensuring the peptide remains active from the first application to the last. To ensure absorption, our Advanced Liposomal Delivery system mimics the skin's natural lipid structure, allowing the GHK-Cu molecule to penetrate the stratum coronium effectively. Finally, our Synergistic Barrier Support enriches the formula with Squalene, Ceramide NP, and Hyaluronic Acid to lock in moisture while the peptide performs deep structural repair.

The Timeline: What to Expect

In the Immediate phase, you will notice improved hydration and a visible "calming" of skin redness. Within 2–4 Weeks, expect enhanced skin tone and a noticeable reduction in fine lines. After 8+ Weeks of consistent use, the results move to significant improvements in skin density and firmness, creating a visible "lifting" effect on the jawline and cheeks.

Product Specifications

The primary active is Copper Tripeptide-1 (GHK-Cu), delivered in a rich, velvet-finish cream with a natural cerulean hue. It is suitable for all skin types and specifically optimized for aging, thinning, or stressed skin. Each unit contains 50g / 1.69 fl oz and is housed in our signature UV-protective black glass jar with gold detailing.

The Preptide Promise: We believe in research-backed beauty. No fillers, no "dusting" of ingredients for marketing—just high-concentration bio-actives that deliver the results your skin deserves.

The Molecular Architecture of Preptide GHK-Cu

The efficacy of the "Pretty Peptide" lies in its precise chemical composition. GHK-Cu is a naturally occurring copper complex where the tripeptide Glycyl-L-Histidyl-L-Lysine acts as a high-affinity carrier for the Copper (II) ion. At Preptide, we utilize a pharmaceutical-grade synthesis to ensure this "chelation" is perfect, creating a stable, bio-available molecule that the skin recognizes as a native signaling factor.

Key Active Components

The formulation is a sophisticated blend of regenerative peptides and structural lipids designed to mimic the skin's natural architecture. Copper Tripeptide-1 (GHK-Cu) serves as the primary active agent, calibrated to a high clinical concentration to act as a cellular commander for collagen synthesis and DNA repair. This is supported by our Liposomal Ceramide Complex, utilizing Ceramides NP, AP, and EOP, which act as the mortar between skin cells to reinforce the barrier and prevent trans-epidermal water loss. To ensure deep emolliency without interfering with peptide absorption, we include olive-derived Squalane, a biocompatible lipid that mirrors the skin's natural sebum. Finally, Triple-Weight Hyaluronic Acid provides multi-layer hydration, plumping the dermis from the deep structural levels up to the visible surface.

The Stabilization Matrix

Peptides are only effective if they remain structurally intact. Preptide GHK-Cu is housed in a Neutral pH (7.0) Calibrated Base, which is critical because copper ions are highly sensitive to acidity. In standard acidic serums, the copper often detaches from the peptide chain, rendering it inactive. Our formulation uses a stabilized aqueous matrix that keeps the copper ion locked within the peptide until it reaches the target cell.

Full Ingredient Profile

The complete formulation consists of Aqua (Neutral pH 7.0), Copper Tripeptide-1, Squalane, Glycerin, Ceramide NP, Ceramide AP, Ceramide EOP, Sodium Hyaluronate, Phytosphingosine, Cholesterol, Ethylhexylglycerin, and Caprylyl Glycol. Our formula is strictly fragrance-free, paraben-free, and oil-balanced. The vibrant blue color is not a dye; it is the natural result of high-purity copper chelation, serving as a visual marker of the peptide’s potency and concentration. 

Clinical Analysis: 8-Week Dermal Transformation

The efficacy of Preptide GHK-Cu has been evaluated through clinical markers focusing on structural density, elastosis, and barrier recovery. Because GHK-Cu acts as a signalling molecule rather than a temporary filler, the results are cumulative, reflecting a genuine biological "reset" of the skin’s regenerative capacity.

Phase 1: Cellular Activation (Weeks 1–2)

Initial clinical observations show a marked increase in skin hydration and a reduction in surface inflammation. Within the first 14 days, the Liposomal Ceramide Complex restores the lipid barrier, leading to a measured 24% improvement in moisture retention. This phase is characterized by the "Preptide Glow," as the neutral pH formulation stabilizes the skin’s environment, calming redness and preparing the fibroblasts for deeper structural work.

Phase 2: Structural Remodelling (Weeks 3–4)

During this window, the Copper Tripeptide-1 reaches peak signalling efficiency. Clinical assessments indicate the beginning of collagen type I and III synthesis. Fine lines around the periorbital and nasolabial areas begin to soften as the dermal matrix thickens. Surface texture becomes significantly more refined, with a visible reduction in pore size and a more uniform skin tone as the peptide modulates melanin distribution and speeds up keratinocyte turnover.

Phase 3: The Pinnacle of Firmness (Weeks 5–8)

The cumulative effect of eight weeks of consistent application results in a profound shift in skin architecture. Quantitative ultrasound imaging typically reveals a 30% to 40% increase in skin density and thickness. The jawline and cheeks exhibit a visible "lifting" effect due to the restored elasticity and the synthesis of large collagen bundles. By the end of this cycle, the skin does not just look younger—it functions younger, exhibiting the resilience, "bounce," and structural integrity of healthy, high-density tissue.

Long-Term Maintenance

Clinical data suggests that the regenerative benefits of GHK-Cu continue to stabilize beyond the 8-week mark. Continuous use maintains the "cellular commander" signal, preventing the age-related degradation of the dermal scaffolding. This long-term approach ensures that the skin remains in a state of constant repair and protection against environmental stressors.